PrimePCR™ ddPCR™ Expression Probe Assay: FBXW11, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0049589; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191753
Chromosome Location:   5:171326934-171327032question
Amplicon Length:   69

Gene Information

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box) which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains Fbls containing leucine-rich repeats and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and in addition to an F-box contains multiple WD40 repeats. This gene contains at least 14 exons and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons. [provided by RefSeq Jul 2008]

Gene Symbol:   FBXW11
Gene Name:   F-box and WD repeat domain containing 11
Aliases:   BTRC2, BTRCP2, FBW1B, FBXW1B, Fbw11, Hos, KIAA0696
RefSeq:   NC_000005.9 NG_009275.1 NT_023133.13
Ensembl:   ENSG00000072803
Entrez:   23291
UniGene:   Hs.484138
Chromosome Mapping:   5q35.1

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