PrimePCR™ ddPCR™ Expression Probe Assay: GPS2, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0041418; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191556
Chromosome Location:   17:7216887-7217012question
Amplicon Length:   96

Gene Information

This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq Jul 2008]

Gene Symbol:   GPS2
Gene Name:   G protein pathway suppressor 2
Aliases:   AMF-1, MGC104294, MGC119287, MGC119288, MGC119289
RefSeq:   NC_000017.10 NT_010718.16
Ensembl:   ENSG00000132522
Entrez:   2874
UniGene:   Hs.438219
Chromosome Mapping:   17p13

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