PrimePCR™ ddPCR™ Expression Probe Assay: BAK1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0041364; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191529
Chromosome Location:   6:33541477-33541681question
Amplicon Length:   175

Gene Information

The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. [provided by RefSeq Jul 2008]

Gene Symbol:   BAK1
Gene Name:   BCL2-antagonist/killer 1
Aliases:   BAK, BAK-LIKE, BCL2L7, CDN1, MGC117255, MGC3887
RefSeq:   NC_000006.11 NT_007592.15
Ensembl:   ENSG00000030110
Entrez:   578
UniGene:   Hs.485139
Chromosome Mapping:   6p21.3

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