PrimePCR™ ddPCR™ Expression Probe Assay: CDK11A, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0041356; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191525
Chromosome Location:   1:1640305-1640486question
Amplicon Length:   66

Gene Information

This gene encodes a member of the p34Cdc2 protein kinase family. p34Cdc2 kinase family members are known to be essential for eukaryotic cell cycle control. This gene is in close proximity to CDC2L1 a nearly identical gene in the same chromosomal region. The gene loci including this gene CDC2L1 as well as metalloprotease MMP21/22 consist of two identical tandemly linked genomic regions which are thought to be a part of the larger region that has been duplicated. This gene and CDC2L1 were shown to be deleted or altered frequently in neuroblastoma with amplified MYCN genes. The protein kinase encoded by this gene could be cleaved by caspases and was demonstrated to play roles in cell apoptosis. Many transcript variants encoding several different isoforms have been found for this gene but the full-length nature of only two have been determined so far. [provided by RefSeq Jul 2008]

Gene Symbol:   CDK11A
Gene Name:   cyclin-dependent kinase 11A
Aliases:   CDC2L2, CDC2L3, CDK11-p110, CDK11-p46, CDK11-p58, MGC131975, PITSLRE, p58GTA
RefSeq:   NC_000001.10 NT_004350.19
Ensembl:   ENSG00000008128
Entrez:   728642
UniGene:   Hs.651228
Chromosome Mapping:   1p36.33

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