PrimePCR™ ddPCR™ Expression Probe Assay: CKMT1A, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0041121; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191418
Chromosome Location:   15:43986205-43986300question
Amplicon Length:   66

Gene Information

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes sarcomeric MtCK and ubiquitous MtCK encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq Jul 2008]

Gene Symbol:   CKMT1A
Gene Name:   creatine kinase, mitochondrial 1A
Aliases:   CKMT1, CKMT1B, FLJ50967, UMTCK
RefSeq:   NC_000015.9 NG_005156.1 NT_010194.17
Ensembl:   ENSG00000223572
Entrez:   548596
UniGene:   Hs.654988
Chromosome Mapping:   15q15

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