PrimePCR™ ddPCR™ Expression Probe Assay: MRPL53, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0041065; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191347
Chromosome Location:   2:74699128-74699253question
Amplicon Length:   96

Gene Information

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species the proteins comprising the mitoribosome differ greatly in sequence and sometimes in biochemical properties which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 1p. [provided by RefSeq Jul 2008]

Gene Symbol:   MRPL53
Gene Name:   mitochondrial ribosomal protein L53
Aliases:   FLJ90728, L53MT, MGC20402
RefSeq:   NC_000002.11 NT_022184.15
Ensembl:   ENSG00000204822
Entrez:   116540
UniGene:   Hs.534527
Chromosome Mapping:   2p13.1

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