PrimePCR™ ddPCR™ Expression Probe Assay: POU5F1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0041056; exonic

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191335
Chromosome Location:   6:31132365-31132494question
Amplicon Length:   100

Gene Information

This gene encodes a transcription factor containing a POU homeodomain. This transcription factor plays a role in embryonic development especially during early embryogenesis and it is necessary for embryonic stem cell pluripotency. A translocation of this gene with the Ewing's sarcoma gene t(6;22)(p21;q12) has been linked to tumor formation. Alternative splicing as well as usage of alternative translation initiation codons results in multiple isoforms one of which initiates at a non-AUG (CUG) start codon. Related pseudogenes have been identified on chromosomes 1 3 8 10 and 12. [provided by RefSeq Mar 2010]

Gene Symbol:   POU5F1
Gene Name:   POU class 5 homeobox 1
Aliases:   MGC22487, OCT3, OCT4, OTF-3, OTF3, OTF4, Oct-3, Oct-4
RefSeq:   NC_000006.11 NT_007592.15 NT_113891.2 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1 NT_167249.1
Ensembl:   ENSG00000204531
Entrez:   5460
UniGene:   Hs.249184
Chromosome Mapping:   6p21.31

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