PrimePCR™ ddPCR™ Expression Probe Assay: LDB3, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0040415; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5191017
Chromosome Location:   10:88439184-88439849question
Amplicon Length:   72

Gene Information

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified; all isoforms have N-terminal PDZ domains while only longer isoforms (1 2 and 5) have C-terminal LIM domains. [provided by RefSeq Jan 2010]

Gene Symbol:   LDB3
Gene Name:   LIM domain binding 3
Aliases:   CMD1C, CYPHER, FLJ35865, KIAA01613, KIAA0613, LDB3Z1, LDB3Z4, LVNC3, ORACLE, PDLIM6, ZASP
RefSeq:   NC_000010.10 NT_030059.13 NG_008876.1
Ensembl:   ENSG00000122367
Entrez:   11155
UniGene:   Hs.657271
Chromosome Mapping:   10q22.3-q23.2

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