PrimePCR™ ddPCR™ Expression Probe Assay: TNF, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0040184; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5190841
Chromosome Location:   6:31545204-31545328question
Amplicon Length:   95

Gene Information

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation differentiation apoptosis lipid metabolism and coagulation. This cytokine has been implicated in a variety of diseases including autoimmune diseases insulin resistance and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine. [provided by RefSeq Jul 2008]

Gene Symbol:   TNF
Gene Name:   tumor necrosis factor
Aliases:   DIF, TNF-alpha, TNFA, TNFSF2
RefSeq:   NC_000006.11 NG_007462.1 NG_012010.1 NT_007592.15 NT_113891.2 NT_167244.1 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1 NT_167249.1
Ensembl:   ENSG00000232810
Entrez:   7124
UniGene:   Hs.241570
Chromosome Mapping:   6p21.3

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