PrimePCR™ ddPCR™ Expression Probe Assay: HLA-F, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0040079; exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5190675
Chromosome Location:   6:29691603-29691952question
Amplicon Length:   74

Gene Information

This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains this molecule is localized in the endoplasmic reticulum and Golgi apparatus with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site resulting in a shorter cytoplasmic domain. [provided by RefSeq Jul 2008]

Gene Symbol:   HLA-F
Gene Name:   major histocompatibility complex, class I, F
Aliases:   CDA12, HLA-5.4, HLA-CDA12, HLAF
RefSeq:   NC_000006.11 NT_007592.15 NT_113891.2 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1 NT_167249.1 NG_012009.1
Ensembl:   ENSG00000204642
Entrez:   3134
UniGene:   Hs.519972
Chromosome Mapping:   6p21.3

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