PrimePCR™ ddPCR™ Expression Probe Assay: HLA-DRA, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0040019; exonic

Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5190586
Chromosome Location:   6:32412568-32412716question
Amplicon Length:   119

Gene Information

HLA-DRA is one of the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha and a beta chain both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes dendritic cells macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon 1 encodes the leader peptide exons 2 and 3 encode the two extracellular domains and exon 4 encodes the transmembrane domain and the cytoplasmic tail. DRA does not have polymorphisms in the peptide binding part and acts as the sole alpha chain for DRB1 DRB3 DRB4 and DRB5. [provided by RefSeq Jul 2008]

Gene Symbol:   HLA-DRA
Gene Name:   major histocompatibility complex, class II, DR alpha
Aliases:   FLJ51114, HLA-DRA1, MLRW
RefSeq:   NC_000006.11 NG_002392.2 NT_007592.15 NT_113891.2 NT_167245.1 NT_167246.1 NT_167247.1 NT_167248.1 NT_167249.1
Ensembl:   ENSG00000204287
Entrez:   3122
UniGene:   Hs.520048
Chromosome Mapping:   6p21.3

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