PrimePCR™ ddPCR™ Expression Probe Assay: SPANXA1, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0039992; exonic

 
Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5190541
Chromosome Location:   X:140671917-140672057question
Amplicon Length:   111

Gene Information

Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family of cancer/testis-associated genes which are located in a cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene maps to chromosome X in a head-to-head orientation with SPANX family member A2 which appears to be a duplication of the A1 locus. The protein encoded by this gene targets to the nucleus where it associates with nuclear vacuoles and the redundant nuclear envelope. Based on its association with these poorly characterized regions of the sperm nucleus this protein provides a biochemical marker to study unique structures in spermatazoa while attempting to further define its role in spermatogenesis. [provided by RefSeq Jul 2008]

Gene Symbol:   SPANXA1
Gene Name:   sperm protein associated with the nucleus, X-linked, family member A1
Aliases:   CT11.1, NAP-X, SPAN-Xa, SPAN-Xb, SPANX, SPANX-A2, SPANX-C, SPANX-D, SPANXA2, SPANXC, SPANXD
RefSeq:   NC_000023.10 NT_011786.16
Ensembl:   ENSG00000198021
Entrez:   30014
UniGene:   Hs.334464
Chromosome Mapping:   Xq27.1

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