PrimePCR™ ddPCR™ Expression Probe Assay: CRK, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCEP0039476; exonic

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5190248
Chromosome Location:   17:1326061-1326200question
Amplicon Length:   110

Gene Information

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq Jul 2008]

Gene Symbol:   CRK
Gene Name:   v-crk sarcoma virus CT10 oncogene homolog (avian)
Aliases:   CRKII
RefSeq:   NC_000017.10 NT_010718.16
Ensembl:   ENSG00000167193
Entrez:   1398
UniGene:   Hs.461896
Chromosome Mapping:   17p13.3

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