PrimePCR™ ddPCR™ Expression Probe Assay: SOCS1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCEP0024407; Exonic

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5190033
Chromosome Location:   16:11349223-11349323question
Amplicon Length:   71

Gene Information

This gene encodes a member of the STAT-induced STAT inhibitor (SSI) also known as suppressor of cytokine signaling (SOCS) family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines including IL2 IL3 erythropoietin (EPO) CSF2/GM-CSF and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action which is required for normal postnatal growth and survival. [provided by RefSeq Jul 2008]

Gene Symbol:   SOCS1
Gene Name:   suppressor of cytokine signaling 1
Aliases:   CIS1, CISH1, JAB, SOCS-1, SSI-1, SSI1, TIP3
RefSeq:   NC_000016.9 NT_010393.16
Ensembl:   ENSG00000185338
Entrez:   8651
UniGene:   Hs.50640
Chromosome Mapping:   16p13.13

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