PrimePCR™ ddPCR™ Expression Probe Assay: RUNX1T1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0041276; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5059136
Chromosome Location:   8:93026907-93029478question
Amplicon Length:   137

Gene Information

This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(8;21)(q22;q22) translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. [provided by RefSeq Nov 2010]

Gene Symbol:   RUNX1T1
Gene Name:   runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
Aliases:   AML1T1, CBFA2T1, CDR, DKFZp564B213, ETO, FLJ33145, MGC2796, MTG8, ZMYND2
RefSeq:   NC_000008.10 NT_008046.16 NG_023272.1
Ensembl:   ENSG00000079102
Entrez:   862
UniGene:   Hs.368431
Chromosome Mapping:   8q22

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