PrimePCR™ ddPCR™ Expression Probe Assay: RAB6A, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0040913; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5059093
Chromosome Location:   11:73431891-73471623question
Amplicon Length:   95

Gene Information

This gene encodes a member of the RAB family which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1 which interacts with the HCMV virion tegument protein pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Aug 2011]

Gene Symbol:   RAB6A
Gene Name:   RAB6A, member RAS oncogene family
Aliases:   RAB6, RAB6A', RAB6B
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000175582
Entrez:   5870
UniGene:   Hs.503222
Chromosome Mapping:   11q13.3

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