PrimePCR™ ddPCR™ Expression Probe Assay: PPP2R1B, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0040778; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5059066
Chromosome Location:   11:111614202-111622955question
Amplicon Length:   157

Gene Information

This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme which is composed of a catalytic subunit and a constant regulatory subunit that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described. [provided by RefSeq Apr 2010]

Gene Symbol:   PPP2R1B
Gene Name:   protein phosphatase 2, regulatory subunit A, beta
Aliases:   MGC26454, PP2A-Abeta, PR65B
RefSeq:   NC_000011.9 NT_033899.8 NG_012117.1
Ensembl:   ENSG00000137713
Entrez:   5519
UniGene:   Hs.584790
Chromosome Mapping:   11q23.2

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