PrimePCR™ ddPCR™ Expression Probe Assay: FUT3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0040619; Intron-spanning

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5059012
Chromosome Location:   19:5844738-5846497question
Amplicon Length:   156

Gene Information

The Lewis histo-blood group system comprises a set of fucosylated glycosphingolipids that are synthesized by exocrine epithelial cells and circulate in body fluids. The glycosphingolipids function in embryogenesis tissue differentiation tumor metastasis inflammation and bacterial adhesion. They are secondarily absorbed to red blood cells giving rise to their Lewis phenotype. This gene is a member of the fucosyltransferase family which catalyzes the addition of fucose to precursor polysaccharides in the last step of Lewis antigen biosynthesis. It encodes an enzyme with alpha(13)-fucosyltransferase and alpha(14)-fucosyltransferase activities. Mutations in this gene are responsible for the majority of Lewis antigen-negative phenotypes. Multiple alternatively spliced variants encoding the same protein have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   FUT3
Gene Name:   fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
Aliases:   CD174, FT3B, FucT-III, LE, Les, MGC131739
RefSeq:   NC_000019.9 NG_007482.1 NG_007505.1 NT_011255.14
Ensembl:   ENSG00000171124
Entrez:   2525
UniGene:   Hs.169238
Chromosome Mapping:   19p13.3

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