PrimePCR™ ddPCR™ Expression Probe Assay: CHEK1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0040478; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5058904
Chromosome Location:   11:125499286-125503126question
Amplicon Length:   109

Gene Information

The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR two cell cycle proteins involved in DNA damage responses that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Oct 2011]

Gene Symbol:   CHEK1
Gene Name:   CHK1 checkpoint homolog (S. pombe)
Aliases:   CHK1
RefSeq:   NC_000011.9 NT_033899.8
Ensembl:   ENSG00000149554
Entrez:   1111
UniGene:   Hs.24529
Chromosome Mapping:   11q24.2

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