PrimePCR™ ddPCR™ Expression Probe Assay: OGDH, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0040471; Intron-spanning

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5058892
Chromosome Location:   7:44706403-44713455question
Amplicon Length:   88

Gene Information

This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex. This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO(2) during the Krebs cycle. The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor. A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia metabolic acidosis and hyperlactatemia. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq Sep 2009]

Gene Symbol:   OGDH
Gene Name:   oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
Aliases:   AKGDH, E1k, OGDC
RefSeq:   NC_000007.13 NT_007819.17 NG_023260.1
Ensembl:   ENSG00000105953
Entrez:   4967
UniGene:   Hs.488181
Chromosome Mapping:   7p14-p13

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