PrimePCR™ ddPCR™ Expression Probe Assay: EDARADD, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0039636; Intron-spanning

Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5058768
Chromosome Location:   1:236577560-236631539question
Amplicon Length:   77

Gene Information

This gene was identified by its association with ectodermal dysplasia a genetic disorder characterized by defective development of hair teeth and eccrine sweat glands. The protein encoded by this gene is a death domain-containing protein and is found to interact with EDAR a death domain receptor known to be required for the development of hair teeth and other ectodermal derivatives. This protein and EDAR are coexpressed in epithelial cells during the formation of hair follicles and teeth. Through its interaction with EDAR this protein acts as an adaptor and links the receptor to downstream signaling pathways. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   EDARADD
Gene Name:   EDAR-associated death domain
Aliases:   ED3, EDA3
RefSeq:   NC_000001.10 NT_167186.1 NG_011566.1
Ensembl:   ENSG00000186197
Entrez:   128178
UniGene:   Hs.732679
Chromosome Mapping:   1q42.3

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