PrimePCR™ ddPCR™ Expression Probe Assay: TPM1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0039314; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5058578
Chromosome Location:   15:63349212-63351804question
Amplicon Length:   119

Gene Information

This gene is a member of the tropomyosin family of highly conserved widely distributed actin-binding proteins involved in the contractile system of striated and smooth muscles and the cytoskeleton of non-muscle cells. Tropomyosin is composed of two alpha-helical chains arranged as a coiled-coil. It is polymerized end to end along the two grooves of actin filaments and provides stability to the filaments. The encoded protein is one type of alpha helical chain that forms the predominant tropomyosin of striated muscle where it also functions in association with the troponin complex to regulate the calcium-dependent interaction of actin and myosin during muscle contraction. In smooth muscle and non-muscle cells alternatively spliced transcript variants encoding a range of isoforms have been described. Mutations in this gene are associated with type 3 familial hypertrophic cardiomyopathy. [provided by RefSeq Jul 2008]

Gene Symbol:   TPM1
Gene Name:   tropomyosin 1 (alpha)
Aliases:   C15orf13, CMD1Y, CMH3, HTM-alpha, TMSA
RefSeq:   NC_000015.9 NT_010194.17 NG_007557.1
Ensembl:   ENSG00000140416
Entrez:   7168
UniGene:   Hs.133892
Chromosome Mapping:   15q22.1

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