PrimePCR™ ddPCR™ Expression Probe Assay: ATP6V1B1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0039162; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5058480
Chromosome Location:   2:71186201-71187179question
Amplicon Length:   106

Gene Information

This gene encodes a component of vacuolar ATPase (V-ATPase) a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting zymogen activation receptor-mediated endocytosis and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits two G subunits plus the C D E F and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a c c' c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of two V1 domain B subunit isoforms and is found in the kidney. Mutations in this gene cause distal renal tubular acidosis associated with sensorineural deafness. [provided by RefSeq Jul 2008]

Gene Symbol:   ATP6V1B1
Gene Name:   ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
Aliases:   ATP6B1, MGC32642, RTA1B, VATB, VMA2, VPP3
RefSeq:   NC_000002.11 NG_008016.1 NT_022184.15
Ensembl:   ENSG00000116039
Entrez:   525
UniGene:   Hs.64173
Chromosome Mapping:   2p13.1

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