PrimePCR™ ddPCR™ Expression Probe Assay: FH, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0039077; Intron-spanning

 
Fluorophore:   HEX
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5058427
Chromosome Location:   1:241675356-241676964question
Amplicon Length:   120

Gene Information

The protein encoded by this gene is an enzymatic component of the tricarboxylic acid (TCA) cycle or Krebs cycle and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extended form differing only in the translation start site used. The N-terminal extended form is targeted to the mitochondrion where the removal of the extension generates the same form as in the cytoplasm. It is similar to some thermostable class II fumarases and functions as a homotetramer. Mutations in this gene can cause fumarase deficiency and lead to progressive encephalopathy. [provided by RefSeq Jul 2008]

Gene Symbol:   FH
Gene Name:   fumarate hydratase
Aliases:   HLRCC, LRCC, MCL, MCUL1
RefSeq:   NC_000001.10 NG_012338.1 NT_167186.1
Ensembl:   ENSG00000091483
Entrez:   2271
UniGene:   Hs.592490
Chromosome Mapping:   1q42.1

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