PrimePCR™ ddPCR™ Expression Probe Assay: TIMP2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033647; Intron-spanning

 
Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5058146
Chromosome Location:   17:76853703-76869940question
Amplicon Length:   145

Gene Information

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq Jul 2008]

Gene Symbol:   TIMP2
Gene Name:   TIMP metallopeptidase inhibitor 2
Aliases:   CSC-21K
RefSeq:   NC_000017.10 NT_010783.15
Ensembl:   ENSG00000035862
Entrez:   7077
UniGene:   Hs.633514
Chromosome Mapping:   17q25

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