PrimePCR™ ddPCR™ Expression Probe Assay: MAP3K7, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033392; Intron-spanning

Fluorophore:   FAM
List Price:    $201.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057910
Chromosome Location:   6:91257815-91261777question
Amplicon Length:   143

Gene Information

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP) and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1 this protein forms a kinase complex including TRAF6 MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK MAP2K4/MKK4 and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq Jul 2008]

Gene Symbol:   MAP3K7
Gene Name:   mitogen-activated protein kinase kinase kinase 7
Aliases:   MEKK7, TAK1, TGF1a
RefSeq:   NC_000006.11 NT_007299.13 NG_011966.1
Ensembl:   ENSG00000135341
Entrez:   6885
UniGene:   Hs.644143
Chromosome Mapping:   6q15

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