PrimePCR™ ddPCR™ Expression Probe Assay: MXI1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033353; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057874
Chromosome Location:   10:112039760-112044662question
Amplicon Length:   135

Gene Information

Expression of the c-myc gene which produces an oncogenic transcription factor is tightly regulated in normal cells but is frequently deregulated in human cancers. The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function and is therefore a potential tumor suppressor. This protein inhibits the transcriptional activity of MYC by competing for MAX another basic helix-loop-helix protein that binds to MYC and is required for its function. Defects in this gene are frequently found in patients with prostate tumors. Three alternatively spliced transcripts encoding different isoforms have been described. Additional alternatively spliced transcripts may exist but the products of these transcripts have not been verified experimentally. [provided by RefSeq Jul 2008]

Gene Symbol:   MXI1
Gene Name:   MAX interactor 1
Aliases:   MAD2, MGC43220, MXD2, MXI, bHLHc11
RefSeq:   NC_000010.10 NT_030059.13 NG_012103.1
Ensembl:   ENSG00000119950
Entrez:   4601
UniGene:   Hs.731767
Chromosome Mapping:   10q24-q25

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