PrimePCR™ ddPCR™ Expression Probe Assay: CAV1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0033323; Intron-spanning

 
Fluorophore:   HEX
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057843
Chromosome Location:   7:116166701-116199093question
Amplicon Length:   107

Gene Information

The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq Mar 2010]

Gene Symbol:   CAV1
Gene Name:   caveolin 1, caveolae protein, 22kDa
Aliases:   BSCL3, CGL3, MSTP085, VIP21
RefSeq:   NC_000007.13 NT_007933.15 NG_012051.1
Ensembl:   ENSG00000105974
Entrez:   857
UniGene:   Hs.74034
Chromosome Mapping:   7q31.1

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