PrimePCR™ ddPCR™ Expression Probe Assay: MMP11, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033306; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057816
Chromosome Location:   22:24121519-24122629question
Amplicon Length:   139

Gene Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However the enzyme encoded by this gene is activated intracellularly by furin within the constitutive secretory pathway. Also in contrast to other MMP's this enzyme cleaves alpha 1-proteinase inhibitor but weakly degrades structural proteins of the extracellular matrix. [provided by RefSeq Jul 2008]

Gene Symbol:   MMP11
Gene Name:   matrix metallopeptidase 11 (stromelysin 3)
Aliases:   SL-3, ST3, STMY3
RefSeq:   NC_000022.10 NG_009303.1 NT_011520.12
Ensembl:   ENSG00000099953
Entrez:   4320
UniGene:   Hs.143751
Chromosome Mapping:   22q11.2,22q11.23

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