PrimePCR™ ddPCR™ Expression Probe Assay: DDB1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033098; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057574
Chromosome Location:   11:61097476-61099052question
Amplicon Length:   79

Gene Information

This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in the patients with xeroderma pigmentosum complementation group E (XPE). However it remains for mutation analysis to demonstrate whether the defect in XPE patients is in this gene or the gene encoding the small subunit. In addition Best vitelliform mascular dystrophy is mapped to the same region as this gene on 11q but no sequence alternations of this gene are demonstrated in Best disease patients. [provided by RefSeq Jul 2008]

Gene Symbol:   DDB1
Gene Name:   damage-specific DNA binding protein 1, 127kDa
Aliases:   DDBA, UV-DDB1, XAP1, XPCE, XPE, XPE-BF
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000167986
Entrez:   1642
UniGene:   Hs.290758
Chromosome Mapping:   11q12-q13

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