PrimePCR™ ddPCR™ Expression Probe Assay: SHANK2, Human

PrimePCR

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033063; Intron-spanning

 
Fluorophore:   FAM
List Price:    $201.00
Your Price:   Log In
 

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057524
Chromosome Location:   11:70505982-70544812question
Amplicon Length:   148

Gene Information

This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction including ankyrin repeats an SH3 domain a PSD-95/Dlg/ZO-1 domain a sterile alpha motif domain and a proline-rich region. This particular family member contains a PDZ domain a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain. Two alternative splice variants encoding distinct isoforms are reported. Additional splice variants exist but their full-length nature has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   SHANK2
Gene Name:   SH3 and multiple ankyrin repeat domains 2
Aliases:   AUTS17, CORTBP1, CTTNBP1, ProSAP1, SHANK, SPANK-3
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000162105
Entrez:   22941
UniGene:   Hs.268726
Chromosome Mapping:   11q13.2

Number Description Download