PrimePCR™ ddPCR™ Expression Probe Assay: RCAN1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033054; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057512
Chromosome Location:   21:35890472-35893857question
Amplicon Length:   114

Gene Information

The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   RCAN1
Gene Name:   regulator of calcineurin 1
Aliases:   ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1
RefSeq:   NC_000021.8 NG_007071.1 NT_011512.11
Ensembl:   ENSG00000159200
Entrez:   1827
UniGene:   Hs.282326
Chromosome Mapping:   21q22.1-q22.2,21q22.12

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