PrimePCR™ ddPCR™ Expression Probe Assay: BMPR1B, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033008; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057448
Chromosome Location:   4:96025658-96035959question
Amplicon Length:   120

Gene Information

This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors but they require their respective type I receptors for signaling whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq Feb 2012]

Gene Symbol:   BMPR1B
Gene Name:   bone morphogenetic protein receptor, type IB
Aliases:   ALK-6, ALK6, CDw293
RefSeq:   NC_000004.11 NG_009245.1 NT_016354.19
Ensembl:   ENSG00000138696
Entrez:   658
UniGene:   Hs.598475
Chromosome Mapping:   4q22-q24

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