PrimePCR™ ddPCR™ Expression Probe Assay: CYP2C8, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0033001; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057434
Chromosome Location:   10:96802761-96805641question
Amplicon Length:   119

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize many xenobiotics including the anticonvulsive drug mephenytoin benzo(a)pyrene 7-ethyoxycoumarin and the anti-cancer drug taxol. This gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. Several transcript variants encoding a few different isoforms have been found for this gene. [provided by RefSeq Nov 2010]

Gene Symbol:   CYP2C8
Gene Name:   cytochrome P450, family 2, subfamily C, polypeptide 8
Aliases:   CPC8, CYPIIC8, MP-12/MP-20
RefSeq:   NC_000010.10 NG_007972.1 NT_030059.13
Ensembl:   ENSG00000138115
Entrez:   1558
UniGene:   Hs.709188
Chromosome Mapping:   10q23.33

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