PrimePCR™ ddPCR™ Expression Probe Assay: PTK2B, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0032942; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
Your Price:   Log In

Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057346
Chromosome Location:   8:27255282-27277541question
Amplicon Length:   124

Gene Information

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway. The encoded protein may represent an important signaling intermediate between neuropeptide-activated receptors or neurotransmitters that increase calcium flux and the downstream signals that regulate neuronal activity. The encoded protein undergoes rapid tyrosine phosphorylation and activation in response to increases in the intracellular calcium concentration nicotinic acetylcholine receptor activation membrane depolarization or protein kinase C activation. This protein has been shown to bind CRK-associated substrate nephrocystin GTPase regulator associated with FAK and the SH2 domain of GRB2. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   PTK2B
Gene Name:   PTK2B protein tyrosine kinase 2 beta
RefSeq:   NC_000008.10 NG_015827.1 NT_167187.1
Ensembl:   ENSG00000120899
Entrez:   2185
UniGene:   Hs.491322
Chromosome Mapping:   8p21.1

Number Description Download