PrimePCR™ ddPCR™ Expression Probe Assay: VCL, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0032822; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057162
Chromosome Location:   10:75863626-75864902question
Amplicon Length:   125

Gene Information

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene but the biological validity of some variants has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   VCL
Gene Name:   vinculin
Aliases:   CMD1W, CMH15, MVCL
RefSeq:   NC_000010.10 NT_030059.13 NG_008868.1
Ensembl:   ENSG00000035403
Entrez:   7414
UniGene:   Hs.643896
Chromosome Mapping:   10q22.2

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