PrimePCR™ ddPCR™ Expression Probe Assay: SSRP1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0032715; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057114
Chromosome Location:   11:57100945-57102090question
Amplicon Length:   194

Gene Information

The protein encoded by this gene is a subunit of a heterodimer that along with SUPT16H forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described but its full-length nature is not known. [provided by RefSeq Jul 2008]

Gene Symbol:   SSRP1
Gene Name:   structure specific recognition protein 1
Aliases:   FACT, FACT80, T160
RefSeq:   NC_000011.9 NT_167190.1
Ensembl:   ENSG00000149136
Entrez:   6749
UniGene:   Hs.523680
Chromosome Mapping:   11q12

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