PrimePCR™ ddPCR™ Expression Probe Assay: PRR5, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0032662; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057068
Chromosome Location:   22:45130928-45132731question
Amplicon Length:   165

Gene Information

This gene encodes a protein with a proline-rich domain. This gene is located in a region of chromosome 22 reported to contain a tumor suppressor gene that may be involved in breast and colorectal tumorigenesis. The protein is a component of the mammalian target of rapamycin complex 2 (mTORC2) and it regulates platelet-derived growth factor (PDGF) receptor beta expression and PDGF signaling to Akt and S6K1. Alternative splicing and the use of alternative promoters results in transcripts encoding different isoforms. Read-through transcripts from this gene into the downstream Rho GTPase activating protein 8 (ARHGAP8) gene also exist which led to the original description of PRR5 and ARHGAP8 being a single gene. [provided by RefSeq Nov 2010]

Gene Symbol:   PRR5
Gene Name:   proline rich 5 (renal)
Aliases:   FLJ20185, FLJ20185k, PP610, PROTOR-1, PROTOR1
RefSeq:   NC_000022.10 NT_011520.12
Ensembl:   ENSG00000186654
Entrez:   55615
UniGene:   Hs.102336
Chromosome Mapping:   22q13

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