PrimePCR™ ddPCR™ Expression Probe Assay: COX6A1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0032637; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5057046
Chromosome Location:   12:120875907-120876266question
Amplicon Length:   181

Gene Information

Cytochrome c oxidase (COX) the terminal enzyme of the mitochondrial respiratory chain catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1 6 7q21 7q31-32 and 12. However only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented. [provided by RefSeq Jul 2008]

Gene Symbol:   COX6A1
Gene Name:   cytochrome c oxidase subunit VIa polypeptide 1
Aliases:   COX6A, COX6AL, MGC104500
RefSeq:   NC_000012.11 NT_009775.17
Ensembl:   ENSG00000111775
Entrez:   1337
UniGene:   Hs.369624
Chromosome Mapping:   12q24.2,12q24.2

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