PrimePCR™ ddPCR™ Expression Probe Assay: GAB2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031953; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056942
Chromosome Location:   11:77934648-77936212question
Amplicon Length:   104

Gene Information

This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq Nov 2009]

Gene Symbol:   GAB2
Gene Name:   GRB2-associated binding protein 2
Aliases:   KIAA0571
RefSeq:   NC_000011.9 NT_167190.1 NG_016171.1
Ensembl:   ENSG00000033327
Entrez:   9846
UniGene:   Hs.429434
Chromosome Mapping:   11q14.1

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