PrimePCR™ ddPCR™ Expression Probe Assay: NLRP10, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031946; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056928
Chromosome Location:   11:7982812-7984836question
Amplicon Length:   111

Gene Information

Members of the NALP protein family typically contain a NACHT domain a NACHT-associated domain (NAD) a C-terminal leucine-rich repeat (LRR) region and an N-terminal pyrin domain (PYD). The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex the inflammasome that activates the pro-inflammatory caspases caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis. [provided by RefSeq Jul 2008]

Gene Symbol:   NLRP10
Gene Name:   NLR family, pyrin domain containing 10
Aliases:   CLR11.1, NALP10, NOD8, PAN5, PYNOD
RefSeq:   NC_000011.9 NT_009237.18
Ensembl:   ENSG00000182261
Entrez:   338322
UniGene:   Hs.449636
Chromosome Mapping:   11p15.4

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