PrimePCR™ ddPCR™ Expression Probe Assay: CSE1L, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031938; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056916
Chromosome Location:   20:47675005-47679812question
Amplicon Length:   125

Gene Information

Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS while importin-beta mediates translocation through the nuclear pore complex. After translocation RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Jan 2012]

Gene Symbol:   CSE1L
Gene Name:   CSE1 chromosome segregation 1-like (yeast)
Aliases:   CAS, CSE1, MGC117283, MGC130036, MGC130037, XPO2
RefSeq:   NC_000020.10 NT_011362.10
Ensembl:   ENSG00000124207
Entrez:   1434
UniGene:   Hs.90073
Chromosome Mapping:   20q13

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