PrimePCR™ ddPCR™ Expression Probe Assay: ENPP2, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031928; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056900
Chromosome Location:   8:120575207-120577140question
Amplicon Length:   95

Gene Information

The protein encoded by this gene functions as both a phosphodiesterase which cleaves phosphodiester bonds at the 5' end of oligonucleotides and a phospholipase which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq Aug 2008]

Gene Symbol:   ENPP2
Gene Name:   ectonucleotide pyrophosphatase/phosphodiesterase 2
RefSeq:   NC_000008.10 NT_008046.16
Ensembl:   ENSG00000136960
Entrez:   5168
UniGene:   Hs.190977
Chromosome Mapping:   8q24.1

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