PrimePCR™ ddPCR™ Expression Probe Assay: ALOX5AP, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031918; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056881
Chromosome Location:   13:31330083-31338133question
Amplicon Length:   103

Gene Information

This gene encodes a protein which with 5-lipoxygenase is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses including asthma arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq Feb 2011]

Gene Symbol:   ALOX5AP
Gene Name:   arachidonate 5-lipoxygenase-activating protein
Aliases:   FLAP
RefSeq:   NC_000013.10 NG_011963.2 NT_024524.14
Ensembl:   ENSG00000132965
Entrez:   241
UniGene:   Hs.507658
Chromosome Mapping:   13q12

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