PrimePCR™ ddPCR™ Expression Probe Assay: MACC1, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031872; Intron-spanning

Fluorophore:   FAM
List Price:    $277.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056798
Chromosome Location:   7:20199802-20201478question
Amplicon Length:   145

Gene Information

MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR or MET; MIM 164860) pathway which is involved in cellular growth epithelial-mesenchymal transition angiogenesis cell motility invasiveness and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al. 2009 [PubMed 19098908]).[supplied by OMIM Mar 2009]

Gene Symbol:   MACC1
Gene Name:   metastasis associated in colon cancer 1
Aliases:   7A5, SH3BP4L
RefSeq:   NC_000007.13 NT_007819.17
Ensembl:   ENSG00000183742
Entrez:   346389
UniGene:   Hs.598388
Chromosome Mapping:   7p21.1

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