PrimePCR™ ddPCR™ Expression Probe Assay: IGF2R, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031773; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056626
Chromosome Location:   6:160517596-160523630question
Amplicon Length:   112

Gene Information

The protein encoded by this gene is a receptor for both insulin-like growth factor 2 (IGF2) and mannose 6-phosphate (M6P). The IGF2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes the activation of transforming growth factor beta and the degradation of IGF2. While the mouse Igf2r gene shows exclusive expression from the maternal allele imprinting of the human IGF2R gene appears to be polymorphic with only a minority of individuals showing expression from the maternal allele. [provided by RefSeq Oct 2010]

Gene Symbol:   IGF2R
Gene Name:   insulin-like growth factor 2 receptor
Aliases:   CD222, CIMPR, M6P-R, MPR1, MPRI
RefSeq:   NC_000006.11 NG_011785.1 NT_025741.15
Ensembl:   ENSG00000197081
Entrez:   3482
UniGene:   Hs.487062
Chromosome Mapping:   6q26

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