PrimePCR™ ddPCR™ Expression Probe Assay: TMC6, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   HEX; Same primer pair and probe as used in qPCR assay qHsaCIP0031736; Intron-spanning

Fluorophore:   HEX
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056565
Chromosome Location:   17:76118732-76120141question
Amplicon Length:   141

Gene Information

Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs. [provided by RefSeq Jul 2008]

Gene Symbol:   TMC6
Gene Name:   transmembrane channel-like 6
Aliases:   EV1, EVER1, EVIN1, FLJ17776, LAK-4P
RefSeq:   NC_000017.10 NG_007881.1 NT_010783.15 NG_007879.1
Ensembl:   ENSG00000141524
Entrez:   11322
UniGene:   Hs.632227
Chromosome Mapping:   17q25.3

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