PrimePCR™ ddPCR™ Expression Probe Assay: BCAR3, Human


ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031719; Intron-spanning

Fluorophore:   FAM
List Price:    $207.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056532
Chromosome Location:   1:94027863-94032874question
Amplicon Length:   123

Gene Information

Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain a hall mark of cellular tyrosine kinase signaling molecules and is partly homologous to the cell division cycle protein CDC48. [provided by RefSeq Jul 2008]

Gene Symbol:   BCAR3
Gene Name:   breast cancer anti-estrogen resistance 3
Aliases:   KIAA0554, NSP2, SH2D3B
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000137936
Entrez:   8412
UniGene:   Hs.36958
Chromosome Mapping:   1p22.1

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