PrimePCR™ ddPCR™ Expression Probe Assay: SESN1, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031665; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056440
Chromosome Location:   6:109315719-109319790question
Amplicon Length:   139

Gene Information

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq Dec 2010]

Gene Symbol:   SESN1
Gene Name:   sestrin 1
Aliases:   MGC138241, MGC142129, PA26, SEST1
RefSeq:   NC_000006.11 NT_025741.15
Ensembl:   ENSG00000080546
Entrez:   27244
UniGene:   Hs.591336
Chromosome Mapping:   6q21

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