PrimePCR™ ddPCR™ Expression Probe Assay: SAG, Human

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PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

ddPCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

Info:   FAM; Same primer pair and probe as used in qPCR assay qHsaCIP0031587; Intron-spanning

 
Fluorophore:   FAM
List Price:    $195.00
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Assay Information

Technology:   ddPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   dHsaCPE5056298
Chromosome Location:   2:234224725-234227433question
Amplicon Length:   64

Gene Information

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones neurotransmitters or sensory signals. S-arrestin also known as S-antigen is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally S-arrestin is highly antigenic and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease a rare autosomal recessive form of night blindness. [provided by RefSeq Jul 2008]

Gene Symbol:   SAG
Gene Name:   S-antigen; retina and pineal gland (arrestin)
Aliases:   DKFZp686D1084, DKFZp686I1383, RP47, S-AG
RefSeq:   NC_000002.11 NG_009116.1 NT_005120.16
Ensembl:   ENSG00000130561
Entrez:   6295
UniGene:   Hs.32721
Chromosome Mapping:   2q37.1

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